Buy Chemotherapy for Neoplastic Diseases

Buy Chemotherapy for Neoplastic Diseases
Buy Chemotherapy for Neoplastic Diseases
60.1 Which of the following neoplastic diseases is almost
curable by chemotherapy:
A. Bronchogenic carcinoma
B. Choriocarcinoma
C. Malignant melanoma
D. Colorectal carcinoma (p. 769)
60.2 The following anticancer drug has high emetogenic
A. Vincristine
B. Chlorambucil
C. 6-Mercaptopurine
D. Cisplatin (p. 771)
60.3 The following is true of cancer chemotherapy:
Buy Chemotherapy For Neoplastic Diseases
A. Anticancer drugs increase the risk of developing leukaemias and lymphomas several
years later
B. All anticancer drugs are highly emetogenic
C. Growth fraction of cancers is higher than
any nomral tissue of the body
D. All of the above are correct (p. 771)
402 MCQs in Pharmacology 402
60.4 Anticancer drugs weaken host defence by:
A. Damaging respiratory and gut epithelia
B. Inducing granulocytopenia
C. Altering resident microbial flora
D. Both ‘A’ and ‘B’ are correct (p. 770)
60.6 Alkylating agents exert cytotoxic action by inducing:
A. Breakage of DNA strand
B. Cross linking of DNA strands
C. Abnormal pairing of purine and pyrimidine
D. All of the above (p. 771)
60.7 The following is true of cyclophosphamide except:
A. It is highly reactive and a vesicant on contact
B. It is a prodrug
C. It has marked immunosuppressant property
D. It frequently causes alopecia and cystitis
(p. 771)
60.8 The most important target of action of chlorambucil
A. Myeloid tissue
B. Lymphoid tissue
C. Neural tissue
D. Skin (p. 772)
60.4 D 60.5 C 60.6 D 60.7 A 60.8 B
Chemotherapy of Neoplastic Diseases 403
60.9 Methotrexate has the following attributes except:
A. It is cell cycle specific and kills cells in the
S phase
B. Its toxicity primarily affects bone marrow
and epithelial structures
C. Folic acid reverses its toxic effects
D. It is the drug of choice for choriocarcinoma
(p. 773)
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60.10 The following antineoplastic drug is a mitotic
inhibitor and causes metaphase arrest:
A. Busulfan
B. Vincristine
C. Cytarabine
D. Procarbazine
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